SURE-PD3 Study

A randomized, double-blind, placebo-controlled trial of urate-elevating inosine treatment to slow clinical decline in early Parkinson's disease

Do you have Parkinson's disease? Have you been diagnosed within the past 3 years?

If yes to both, you may be a good candidate for a research study.


What is the goal of this study?

The SURE-PD3 study is looking for patients who have early largely untreated Parkinson's disease. We are doing this research study to see if increasing ones own levels of the antioxidant urate can slow the progression of Parkinson's disease (PD). We will increase blood urate levels with a natural supplement called inosine.

You may qualify for the study if you:

  •  Have been diagnosed with PD within the past 3 years.
  •  Are not taking any medication to treat PD (except for MAO-B inhibitors).
  •  Don’t have a history of gout, recurrent kidney stones, heart attack or stroke.

What is involved if I participate?

  • Volunteers will be in this study for about 28 months and will visit the clinic at least 14 times.
  •  If you choose to volunteer and pass several screening tests, you will be randomly assigned to either inosine (active drug) or a placebo (an inactive drug) with an equal chance of receiving either.


If you are interested in participating or want to learn more, please contact Aaron Daley at 415-476-9276 or [email protected]

Study Flyer